KAKEN — Research Projects | Researcher Number: 10273690

Search Results: 11 results / Researcher Number: 10273690

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1. Clinical significance of lymph node metastasis detected by OSNA and its application for breast cancer treated with neoadjuvant chemotherapy

Research Project

Research Category	Grant-in-Aid for Scientific Research (C)
Research Field	General surgery
Research Institution	Research Institute, Osaka Medical Center for Cancer and Cardiovascular Disaeses (2012-2013) Osaka University (2011)
Principal Investigator	TAMAKI Yasuhiro 地方独立行政法人大阪府立病院機構大阪府立成人病センター(研究所), その他部局等, その他(副院長)
Project Period (FY)	2011 – 2013Completed
Keywords	乳癌 / センチネルリンパ節 / OSNA / 術前化学療法 / 転移予測 / センチネルリンパ節生検 / 腋窩リンパ節転移 / サイトケラチン
Research Abstract	Study 1. Usefulness of OSNA for detection of lymph node metastasis in breast cancer patients treated with neoadjuvant chemotherapy was examined. Lymph ...

Research Products of this project	Journal Article (1 results)

2. Multilateral Study of Breast Rewnstnicthn after Mastectomy - QOL and Cost Effectiveness Analysis

Research Project

Research Category	Grant-in-Aid for Scientific Research (C)
Research Field	Plastic surgery
Research Institution	Osaka University
Principal Investigator	YANO Kenji Osaka University, Graduate School of Medicine, Endowed Chair Professor
Project Period (FY)	2006 – 2007Completed
Keywords	Reconstructive Surgery / Breast Sureery / Breast Reconstruction
Research Abstract	(Purpose) Breast reconstruction after mastectomy serves as an insurance indication from April, 2006, and it seems that the perform rate will be shown ...

Research Products of this project	Journal Article (53 results, of which Peer Reviewed: 30 results) Presentation (31 results) Book (4 results)

3. Molecular Diagnosis of Breast Cancer Characteristics for Personalized Medicine

Research Project

Research Category	Grant-in-Aid for Scientific Research on Priority Areas
Review Section	Biological Sciences
Research Institution	Osaka University
Principal Investigator	NOGUCHI Shinzaburo Osaka University
Project Period (FY)	2005 – 2009Completed
Keywords	乳癌 / 予後 / 化学療法感受性 / 遺伝子発現 / 細胞周期 / プロファイリング / 遺伝子発現プロファイル / 細胞周期プロファイリング / 乳がん / 薬剤感受性 / パクリタキセル / 悪性度 / 細胞増殖 / レドックス / タキサン / アンスラサイクリン / 甲状腺癌
Research Abstract	We have been able to construct diagnostic systems for prognosis of breast cancer patients treated with adjuvant hormonal therapy alone, taking advanta ...

Research Products of this project	Journal Article (81 results, of which Peer Reviewed: 65 results) Presentation (12 results)

4. Surgical navigation systems for soft tissues surgery with shape deformation

Research Project

Research Category	Grant-in-Aid for Scientific Research (B)
Research Field	Intelligent informatics
Research Institution	Osaka University
Principal Investigator	SATO Yoshinobu Osaka University Graduate School of Medicine. Associate Professor
Project Period (FY)	2000 – 2002Completed
Keywords	medical images / computer-assisted surgery / soft tissue / 3D ultrasound / shape deformation / magnetic distortion correction
Research Abstract	Surgical navigation systems are becoming eommon, which realize realtime (or rapid) 3D recbnstmction of the operating room and internal anatomical stru ...

Research Products of this project	Publications (40 results)

5. Navigation system for endoscope

Research Project

Research Category	Grant-in-Aid for Scientific Research (B)
Research Field	Biomedical engineering/Biological material science
Research Institution	Osaka University
Principal Investigator	TAMURA Shinichi Osaka University Graduate School of Medicine, Professor
Project Period (FY)	2000 – 2003Completed
Keywords	Intra-body localization / Ultrasound / Endoscope / 3D position sensor / Transducer
Research Abstract	Different from conventional virtual navigation, we have developed two real intra-body navigation systems, which support endoscopic examination and end ...

Research Products of this project	Publications (27 results)

6. Construction of safety gude system for Operation by magnetic particles

Research Project

Research Category	Grant-in-Aid for Scientific Research (B)
Research Field	Biomedical engineering/Biological material science
Research Institution	Toyohashi University of Technology
Principal Investigator	TANAKA Saburo Toyohashi University of Technology, Dep.of Engineering Professor
Project Period (FY)	2000 – 2002Completed
Keywords	SQUID / Lymph Node / Particles
Research Abstract	The performance of a lymph node detection system used with an ultra-small superparamagnetic iron oxide and a high-Tc SQUID was investigated. This syst ...

Research Products of this project	Publications (19 results)

7. 乳がんの遺伝子診断とその臨床応用

Research Project

Research Category	Grant-in-Aid for Scientific Research on Priority Areas
Review Section	Biological Sciences
Research Institution	Osaka University
Principal Investigator	野口眞三郎大阪大学, 医学系研究科, 教授
Project Period (FY)	2000 – 2004Completed
Keywords	乳がん / 遺伝子発現プロファイル / ATAC-PCR / 予後 / 化学療法感受性 / 乳癌 / 遺伝子診断 / 易罹患性 / 微小転移 / 遺伝性乳癌 / 白血病 / WT1 mRNA
Research Abstract	乳癌治療においては、ホルモン療法と化学療法が汎用されるが、最大の問題点はそれらの治療効果を予測し得る正確な指標が存在しないことである。そこで、我々は、ATAC(adaptor tagged competitive)-PCR法による乳癌組織の遺伝子発現プロファイル解析を用いて、新しい乳癌のホルモン療法 ...

Research Products of this project	Journal Article (10 results) Publications (62 results)

8. Clinical Application of Genetic Diagnosis of Breast Cancer

Research Project

Research Category	Grant-in-Aid for Scientific Research (A)
Research Field	General surgery
Research Institution	Osaka University
Principal Investigator	NOGUCHI Shinzaburo Osaka University, Surgical Oncology, Professor
Project Period (FY)	1999 – 2001Completed
Keywords	Breast cancer / Genetic diagnosis / Nucrinetastasis / BRCA1 / BRCA2 / Risk assessment
Research Abstract	Summary of our research intended for clinical application of genetic diagnosis of breast cancer is described below : (1) Differential diagnosis of ben ...

Research Products of this project	Publications (105 results)

9. Application of integrin α4β1 for diagnosis and therapy of bone metastasis

Research Project

Research Category	Grant-in-Aid for Scientific Research (C)
Research Field	Human pathology
Research Institution	Osaka University
Principal Investigator	MATSUURA Nariaki Osaka University, School of Medicine, Professor
Project Period (FY)	1998 – 2000Completed
Keywords	bone metastasis / chemotherapy / integrin α4β1 / transfection
Research Abstract	In the previous study α4-CHO cell, transfectant of integrin α4β1 for Chinese hamster ovary cell, caused prominent bone metastasis in vivo and the inte ...

Research Products of this project	Publications (49 results)

10. 正常脂肪細胞の3次元立体大量培養法の開発-自己脂肪細胞大量移植に関する基礎的研究-

Research Project

Research Category	Grant-in-Aid for Exploratory Research
Research Field	General surgery
Research Institution	Osaka University
Principal Investigator	玉木康博大阪大学, 医学部, 助手
Project Period (FY)	1996Completed
Keywords	脂肪移植 / 立体培養 / 大量培養
Research Abstract	乳癌手術症例の新鮮切除標本より、18G針を用いた脂肪吸引法にて皮下脂肪組織を採取した。採取組織片を生理食塩水にて洗浄後、10%FBS RPMI中でceiling法にて培養した。培養後数日で繊維芽細胞様細胞の湧出がみられ、約2週間後の観察では組織片は脂肪融解により白色に変化し、周囲に繊維芽細胞様細胞が ...

11. 乳癌の増殖進展におけるオキシトシン・オキシトシンレセプターの関与について

Research Project

Research Category	Grant-in-Aid for General Scientific Research (C)
Research Field	General surgery
Research Institution	Osaka University
Principal Investigator	玉木康博大阪大学, 医学部, 助手
Project Period (FY)	1995Completed
Keywords	乳癌 / オキシトシン / オキシトシンレセプター
Research Abstract	乳癌におけるオキシトシン(OT)レセプター(OTR)の発現について新しく作成したモノクローナル抗体を用いて検索した。2F8抗体を用いたWestern blotting法によると70k OTRの発現が妊娠子宮筋および乳癌組織に確認された。免疫組織染色では乳癌患者57名中52名(91.2%)に2F8によ ...

Research Products of this project	Publications (1 results)